Researchers may have found a miraculous cure for baldness – BGR

  • A team of researchers from Japan could have discovered the cure for baldness.
  • The RIKEN Center for Biosystem Dynamics Research has used stem cells and a specific culture mechanism to create hair follicles that can recycle hair just like natural follicles.
  • Any hair regeneration treatment should produce hair that can grow back after it falls out. Stem cell therapy provided hair follicles that went through at least three cycles of normal hair production in laboratory tests.

Many people have tried to cure a condition that affects millions of people around the world, with men being predominantly affected by it. Baldness can be triggered by specific drug therapies, such as cancer treatment, and some COVID-19 survivors have found that hair loss is an unusual symptom. But baldness occurs in many others without a specific trigger. By the age of 35, two-thirds of American men will experience some degree of hair loss, according to the American Hair Loss Association. By the age of 50, up to 85% of men will experience significant hair thinning.

Baldness does not affect one’s health, but it can have an emotional value on those who are affected by it. There are various therapies for baldness, but there is no cure that can reverse the process. Now, however, a team from Japan could have found a solution to restore hair growth with the help of stem cells.

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Researchers have used stem cells to create hair follicles that can regrow hair after it has fallen out. This is how hair growth should work. Hair loss is natural, but each strand of hair should be replaced with a new one that grows in its place. Scientists from the RIKEN Center for Biosystems Dynamics Research have published a paper in Scientific reports on nature (via Futurism) detailing their progress with stem cells in mammals.

They took fur cells and mustaches from the mice and then cultured them in the lab along with other ingredients. They used 220 combinations, finding that a type of collagen associated with five factors (NFFSE medium) would lead to the highest rate of stem cell amplification in the shortest amount of time. The RIKEN team explained that a successful hair regeneration treatment that could cure baldness must produce hair that recycles. This means that the hair can grow back after natural hair loss.

These researchers combined bioengineered hair follicle stem cells with the NFFSE medium, as well as with the medium that lacks one of the ingredients. They observed regenerated hair for three weeks and found that the NFFSE environment allowed hair follicles to go through at least three cycles of normal hair production. The other medium was not nearly as effective, with 79% of the follicles producing a single hair cycle.

The researchers also found that a specific marker on the surface of cells grown in NFFSE medium favored the hair cycle. “We found that almost 80% of follicles reached three hair cycles when Itgβ5 was also bioengineered into the hair follicle germ,” author Makoto Takeo said in a statement. “In contrast, only 13% reached three cycles when not present.”

“Our culture system establishes a method for cyclic regeneration of hair follicles from hair follicle stem cells and will help make hair follicle regeneration therapy a reality in the near future,” said lead author Takashi Tsuji. of the study.

Before this baldness treatment becomes commercially available, it must undergo clinical trials. To date, RIKEN researchers have demonstrated stem cell therapy in preclinical laboratory tests. Tsuji said the institute is looking for external collaborators to help develop clinical applications for new hair growth technology.

The full study is available at this link.

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Chris Smith began writing about gadgets as a hobby, and before he knew it, he was sharing his views on technical stuff with readers around the world. Whenever he doesn’t write about gadgets, he can’t stay away from them, even though he tries desperately. But that’s not necessarily a bad thing.

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