Covid-19 survivors who received a first dose of the Covid-19 vaccine generate immune responses that could make the second shot unnecessary, unleashing the limited vaccination potential for more people, several new research papers suggest.
The research, although preliminary, found that previously infected people generated protection against the disease quickly and at dramatically higher levels after a first shot of the current two-shot regimens compared to people who had been vaccinated but had not been ill.
“Everyone should be vaccinated. Not everyone needs two photos, ”said Viviana Simon, a professor of microbiology at New York’s Icahn School of Medicine in Mount Sinai and author of a study. As long as we can’t deliver as much vaccine as possible to everyone who wants it, I think that’s an important issue. ”
The research, which was posted on prepress servers but not evaluated by colleagues or published in a scientific journal, comes as other findings of the two-photo regimen for healthy members of the general population highlight immune benefits after the first injection. . On Friday, Israeli researchers reported a single vaccine from Pfizer Inc. and BioNTech SE is 85% effective in preventing symptomatic disease 15 to 28 days after administration.
Late-stage clinical trials of two-dose vaccines by Pfizer and BioNTech, as well as Moderna Inc., have been shown to be safe and extremely protective against Covid-19 when given as two doses a few weeks apart. . However, the Pfizer study excluded people with symptomatic Covid-19, and Moderna omitted people with a previously known infection, causing researchers to see how the immune systems responded to previously ill people.