Cellular “atlas” of the skin highlights how psoriasis and eczema develop

by

The cellular “atlas” of the skin sheds light on the development of psoriasis and eczema and could lead to new treatments

  • The researchers created an “atlas” of 50,000 different skin cells
  • Identification of cellular mechanisms that cause chronic skin conditions
  • Many have been found to be the same as in healthy cells and I hope the database and discovery will allow for future therapeutic development.

By PA Media and Joe Pinkstone for Mailonline

Published: | Updated:

Scientists in the UK have discovered how chronic skin conditions develop, such as psoriasis and eczema.

Researchers at the University of Newcastle have found that skin cells with eczema and psoriasis share many of the cellular mechanisms such as the development of healthy skin cells.

The team said the findings, published in the journal Science, could help develop new drugs that target inflammatory skin diseases.

Researchers at Newcastle University have found that skin cells with eczema and psoriasis share many of the cellular mechanisms such as the development of healthy skin cells.

Researchers at Newcastle University have found that skin cells with eczema and psoriasis share many of the cellular mechanisms such as the development of healthy skin cells.

Psoriasis, which affects about two per cent of people in the UK, is caused by an increased production of skin cells.

Although the process is not fully understood, the condition is thought to be related to an immune system problem.

Eczema, which causes the skin to become itchy, dry and cracked, is more common in children, but can improve as they age.

There is no cure for the disease, and treatments can relieve the symptoms.

Scientists have created a detailed map of human skin as part of the global Atlas of Human Cells effort to map every cell type in the human body.

They looked at how cells grow on healthy skin as well as on the skin of patients with eczema and psoriasis.

Psoriasis, which affects about two per cent of people in the UK, is caused by an increased production of skin cells. Although the process is not fully understood, the condition is thought to be related to an immune system problem.

Psoriasis, which affects about two per cent of people in the UK, is caused by an increased production of skin cells. Although the process is not fully understood, the condition is thought to be related to an immune system problem.

Facial masks can trigger ECZEMA seizures in people with sensitive skin and allergies, warns study

People with sensitive skin may be at risk for eczema caused by wearing a face mask.

Doctors revealed that a 60-year-old man with a history of several skin allergies suffered a dermatitis attack caused by a mask.

After initially trying to diagnose the root of the problem, doctors realized that the cause of the elastic bands of his face mask.

The patient was diagnosed with a case of contact dermatitis, a form of eczema fueled by a reaction to a substance or material.

The American man received drugs with prednisone, a common antiallergic drug, before the mask problem was noticed.

But this was ineffective and the man later returned to his doctors with the problem.

After identifying the location on the face in the same place where a mask is located, doctors speculated that the form of PPE may be to blame.

Analysis of more than 500,000 skin cells showed that diseased cells shared many of the same molecular pathways as developing cells.

Professor Muzlifah Haniffa, senior co-author at the University of Newcastle and Associate Faculty at the Wellcome Sanger Institute, said: forms a protective layer.

“We were amazed to see that the eczema and psoriasis skin cells sent the same molecular signals, which could activate the immune cells and cause the disease.

“It simply came to our notice then. The discovery that the development of cellular pathways is reappearing is a huge leap in our understanding of inflammatory skin diseases and offers new ways to find treatments.

The researchers said their study opens new avenues for research into other inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease, and could have “major implications” for regenerative medicine, especially for burn victims.

Professor Fiona Watt, co-lead author at Kings College London, said: “There has been decades of research into laboratory-grown skin cells.

However, it is not always clear how the properties of cells change in the laboratory.

By revealing the detailed makeup of cells immediately after isolation from developing and adult human skin, this atlas of skin cells can act as a template for researchers trying to rebuild healthy skin in regenerative medicine.

.Source