A so-called variant variant of coronavirus R.1 was detected in an outbreak at a Kentucky health care facility, where almost all residents were vaccinated, according to a recent report from the Centers for Disease Control and Prevention ( CDC). Health departments said coronavirus infections occurred in a quarter of vaccinated residents, raising concerns about the impact of the vaccine.
The unnamed qualified healthcare facility has offered vaccination to all residents and staff since January, with 90.4% of 83 residents receiving a vaccine and just over half of employees accepting doses.
A Kentucky Department of Public Health investigation revealed that unvaccinated, infected staff started the outbreak in early March, eventually resulting in 46 COVID-19 cases. A total of 26 residents were infected, including 18 fully vaccinated people and 20 employees, including four vaccinated people.
The report suggested that unvaccinated people face a 3 to 4.1 times higher risk of infection compared to people who accepted strokes.
COVID-19 VACCINE DOES NOT “COME OUT OF FREE CARD FOR PRISONS”, INFECTIONS MAY OCCUR
Recently approved coronavirus vaccines are safe and extremely effective, but they are not 100% effective, the CDC notes, and the agency says it expects cases of discovery or infections in fully vaccinated people. However, the effectiveness of the vaccine has been lower than that seen in the launch of the real-world vaccine in Israel, although the CDC warns against comparing the results due to the small sample size, increased risk and testing, regardless of symptoms in the healthcare unit. from Kentucky.
The vaccine was 86.5% protective in reducing symptomatic disease for residents and 87.1% protective among staff, according to the CDC report. The vaccine has been shown to be more effective in preventing poor results; the effectiveness of the reported vaccine against hospitalizations was over 94% for residents; no staff was hospitalized.
EVALUATION OF THE OXFORD CHALLENGE TEST CORONAVIRUS REINFECTION, IMMUNE RESPONSES
The R.1 lineage variant is not listed in the variants of interest or concern compiled by the CDC, although it includes several mutations observed in other variants that have previously been shown to spread more rapidly and resist antibody treatments.
“Although vaccination was associated with a low likelihood of infection and symptomatic disease, 25.4% of vaccinated residents and 7.1% of vaccinated HCP were infected, raising concerns about the potential reduced protective immunity at R.1” , is shown in the report. In addition, four possible reinfections have been identified, providing some evidence of limited or declining natural immunity to this variant.
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Three residents died, one of whom was vaccinated, and the four possible reinfections were identified among unvaccinated people. All possible cases of reinfection involved symptomatic illness, and a resident was hospitalized and died.
The CDC is calling for COVID-19 vaccination to be provided to health care providers working in qualified health care facilities to protect residents and prevent the transmission of the virus. The report had its limitations, such as potential discrepancies in health status for staff who accepted the vaccine from those who did not, which could distort outcomes that do not control the underlying health conditions. Antigen testing may also have missed some asymptomatic cases, which, if true, would affect the effectiveness of the vaccine.