PFIZER
WHEN WAS IT APPROVED? December 11, 2020
WHO CAN GET IT? Anyone 16 years of age or older
DOSAGE: 2 doses, administered at a distance of 21 days
HOW IT WORKS? Use messenger RNA to provide some genetic code from the virus to “teach” the body to produce a protein that causes the production of antibodies
HOW EFFICIENT IS IT …
AFTER 2 DOSES: 95% effective in disease prevention; 100% effective in preventing death COVID-19; 87% effective in preventing hospitalization
AFTER THE FIRST DOSE: (not recommended) ~ 46% effective in preventing infection seven to 20 days later; 57% effective against symptomatic diseases; 72% effective in preventing death; 74% effective against hospitalization; 62% effective against severe diseases (based on real-world data from Israel)
AGAINST VARIANTS FROM …
United Kingdom – B117: No significant impact
South Africa – B1351: 10% less efficient; still protective
Brazil – P1: Antibodies 10.4 times weaker; still protective
MODERN
WHEN WAS IT APPROVED? December 18, 2020
WHO CAN GET IT? Anyone 18 years of age or older
DOSAGE: 2 doses, administered at a distance of 28 days
HOW IT WORKS? Use messenger RNA to provide some genetic code from the virus to “teach” the body to produce a protein that causes the production of antibodies
HOW EFFICIENT IS IT …
AFTER 2 DOSES: 94% effective in disease prevention; 100% effective in preventing death COVID-19; 89% effective in preventing hospitalization
AFTER THE FIRST DOSE: (not recommended) ~ 80% effective, based on test data
AGAINST VARIANTS FROM …
Great Britain – B117: No significant impact
South Africa – B1351: 10% less efficient; still protective
Brazil – P1: More data required
JOHNSON & JOHNSON
WHEN WAS IT APPROVED? February 27, 2021
WHO CAN GET IT? Anyone 18 years of age or older
DOSAGE: 1 dose
HOW IT WORKS? Use a harmless, cold, inactivated virus to carry a piece of spike protein in the body to teach it to fight SARS-CoV-2
HOW EFFICIENT IS IT …
After a single dose: 72% worldwide; 86% in the USA
AGAINST VARIANTS FROM …
United Kingdom – B117: No significant impact
South Africa – B1351: 64% efficient
Brazil – P1: 85% efficient