The Oxford University coronavirus vaccine induces the best immune response when given in two full doses, the researchers said after publishing additional data from early studies.
The findings were published in Nature Medicine on Thursday, and an accompanying university statement said the vaccine “induces broad antibody and T cell functions.”
“We have shown that booster doses of the vaccine induce stronger antibody responses than a single dose, with the standard dose / standard dose inducing the best response,” the university statement said.
ASTRAZENECA CORONAVIRUS SAFE VACCINE, 70% EFFICIENT, STUDY SUGGESTIONS
The results published in The Lancet last week suggested that the shot was safe and about 70% effective, although a previous confusion led some participants to get half a dose followed by a full dose, instead of two full doses as intended. As a result of the error, preliminary results showed that a half-dose / full-dose regimen was 90% effective and two full doses showed 62% efficacy.
The team of researchers could not explain the discrepancy between the data at first.
The mix has affected confidence in the jab, although experts say it will probably still be approved.
The Associated Press contributed to this report.
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